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The idea is to avoid the common problem seen with GLP 1 weight loss drugs like Wegovy and Mounjaro, where many pic.twitter.com/0ICUH8FdLX Gandalv (@Microinteracti1) January 26, 2026 Biotech company Fractyl Health is preparing clinical trials of a gene therapy called Rejuva, which delivers genetic instructions directly to the pancreas

The first breakthrough confirming this hypothesis pertained to the seemingly antithetical combination of glucagon receptor (GCGR) activity with GLP-1R agonism, as a monomolecular, similarly sized co-agonist 38

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