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Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis. NEJM

The Science Behind Appetite Regulation Semaglutide for weight loss works by enhancing insulin sensitivity and improving glucose metabolism
Most medical guidelines recommend at least 6 to 12 months of consistent use before evaluating long-term continuation

But it's not just about the scale: the SELECT cardiovascular outcomes trial, the largest of its kind, showed a 20% reduction in major cardiovascular events (heart attack, stroke, cardiovascular death) in patients taking semaglutide
