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Longitudinal Analysis of Obesity Drug Use and Public Awareness

Overall, about one in five (22%) adults who are not currently taking GLP-1 drugs (88% of the public) say they would be interested in taking a GLP-1 drug to lose weight, including just 7% who say they would be very interested. This rises to four in ten (43%) among adults who are not currently taking a GLP-1 but report being diagnosed as overweight or obese in the past five years, and about one in four (27%) among those who say they have been diagnosed with diabetes or heart disease

When levels stay low, cravings increase, and weight loss becomes harder

However, BBRs translational applications face biopharmaceutical challenges, including poor intestinal absorption ( 50% in obesity across murine and human models [170,171,172,173]