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Across our addiction and health-behaviors research, were advancing personalized strategies new statistical methods to untangle polysubstance use, brain-based biomarkers to guide care, and tech-in-the-wild experiments that ground lab insights in everyday life. The ongoing research is uncovering how neural pathways and the brains reward system drive substance use disorders, and highlighting new therapies like GLP-1 receptor agonists to curb cravings
Second, polyphenols can directly interact with metabolic signalling pathways including AMPK (a cellular energy sensor) and NF-kB (a master inflammatory regulator)
GLP-1 receptor agonists function by mimicking the action of the naturally occurring GLP-1 hormone
Weina et al., 2018)
