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For example, liraglutide, a GLP-1 receptor agonist, improved cognitive function in n = 19 patients with major depressive disorder (MDD) or bipolar disorder in a pilot randomised controlled trial (RCT) [16], whilst a systematic review and meta-analysis reported a pooled reduction in depressive symptoms with GLP-1 receptor agonists compared to other antidiabetic therapies [17]

These combine sodium with other electrolytes in balanced ratios

Jumping to higher doses too quickly is one of the primary causes of severe gastrointestinal side effects that drive people to abandon treatment entirely