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Respective control mice (lean and ob/ob ) receive saline every 24 hours

Systemic liraglutide administration activated LS GLP-1R neurons, and the knockdown of GLP-1Rs in the LS mitigated the anti-obesity effects of liraglutide

Clinical trials on its active ingredients show continued improvement over 8 to 12 weeks, with users losing an average of 8-14 pounds while maintaining lean mass
Zhang, J
