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Why it matters: A broader mechanism does not automatically mean a safer or better treatment
B1 (thiamine) deficiency has produced some of the most alarming case reports, including Wernicke encephalopathy, a potentially fatal brain condition caused by severe thiamine depletion
Preclinical studies have shown promising results, with GLP-1 agonists demonstrating the ability to protect cartilage and reduce inflammation in animal models of osteoarthritis
People in this group also have a higher risk of developing pulmonary fibrosis, a form of lung scarring
