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Multiple rodent models of PCOS, capitalizing mainly on the impact of androgen excess at different developmental windows, with variable penetrance in terms of reproductive and metabolic impairment, have been used in translational studies, in order to capture the phenotypic heterogeneity of the syndrome 38

12 These sessions should be on non-consecutive days (e.g., Monday/Wednesday/Friday or Tuesday/Thursday) to allow muscles adequate time to recover and rebuild, which is when growth actually occurs

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The hypothalamic-pituitary-ovarian axis, which governs reproductive function, is sensitive to energy availability