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GLP-1 in addiction medicine: GLP-1 acts on pancreas, gut, kidney, heart and thyroid receptors to activate reward/stress hubs (VTA, NAc, ARC, PFC, hypothalamus)
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Metabolic issues may prevent you from making the lasting changes you want, even while following a weight loss plan, and hunger may cause you to snack or eat more than you prefer

GLP-1 receptor (GLP-1R) agonists applied peripherally or centrally decrease food intake and increase glucose-stimulated insulin ...