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Wegovy (semaglutide) is a GLP-1 receptor agonist licensed for chronic weight management in adults with obesity or overweight with comorbidities

They identified 16,058 patients with MASLD and diabetes who initiated GLP-1RAs between January 2006 and June 2022 and matched them to an equal number of patients who initiated dipeptidyl peptidase 4 inhibitors (DPP-4is) in the same month

Figura 1 : Acciones de GLP-1 Efectos de glp1 en pncreas Efecto sobre la secrecin y metabolismo de insulina Acciones sobre la masa de clulas beta Efecto sobre la liplisis de clula beta Efecto sobre la secrecin de glucagn Efecto de GLP1 sobre la secrecin de insulina Como fue sealado previamente las incretinas son hormonas intestinales liberadas dentro de la circulacin luego de la ingestin de alimentos estimulando la secrecin de insulina en forma dependiente de la glucosa

Patients often report reductions in hunger, heightened fullness after meals, diminished cravings, increased energy, and better levels in blood pressure, cholesterol, and blood sugar