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Patients on semaglutide, liraglutide, or tirzepatide should be told that excessive daytime sleepiness is a possible side effect, with an absolute incidence of roughly 0.40.7 percentage points above baseline at 1 to 5 years
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The incretins act through G protein-coupled receptors

Clinical trials show small reductions in total cholesterol, LDL cholesterol, and triglycerides alongside their primary metabolic benefits