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these drugs include glucagon-like peptide-1 (GLP-1) receptor agonists and dipeptidyl peptidase 4 (DPP-4) inhibitors [13, 14]

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Lanifibranor is an oral small molecule that activates all three PPAR isoforms (PPAR, PPAR and PPAR), inducing anti-fibrotic, anti-inflammatory and other beneficial metabolic changes in the body, and delivers these outcomes by decreasing triglyceride levels and increasing high-density lipoprotein cholesterol levels and insulin sensitization (Figure 2)

DPP4 activity but not protein level within the PV was significantly reduced in Dpp4 hep/ mice compared with Dpp4 GFP mice (Figure 2, C and D)