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Description
ZEUS will enrol 6200 participants with stage 3 or 4 CKD and elevated hsCRP levels, with a primary MACE outcome and secondary kidney endpoints including kidney disease progression, UACR reductions and eGFR slope
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For semaglutide, the fatty di-acid chain is attached to Lys26 through one glutamic acid and two 8-amino-3,6-dioxaoctanoic acid (ADO) moieties to achieve the optimal binding affinity [64]
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