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GLP-1based therapies are associated with predictable GI adverse effects, most of which are mild to moderate and manageable
Sitagliptin is the first of a class of drugs to be approved that mimics the actions of the dipeptidyl peptidase-4 (DPP-4) enzyme.

A new blockbuster class of therapeutics, glucagon-like peptide 1 (GLP-1) analogs (eg, semaglutide), shows promise at curbing both diseases
