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The AAPS Journal, 15 (1), 195-218

Targeting the hepatic microenvironment to improve ischemia/reperfusion injury: New insights into the immune and metabolic compartments

Heffernan MA, Thorburn AW, Fam B, et al

The LPS-TLR4-JNK/NF-B axis disrupts mitochondrial membrane potential and cristae architecture while downregulating Parkin expression, thereby blocking PINK1/Parkin-mediated mitochondrial autophagy
