how to dose cagrilintide Three new #obesity drugs—high-dose semaglutide, semaglutide plus cagrilintide, and oral orforglipron—may soon be approved in the US. JAMA Medical News Director Jennifer Abbasi and Lead Senior Staff Writer Rita Rubin examine Unlocking the Power of Cagrilintide:
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Given their non-invasive nature, accessibility, and cost-effectiveness of sublingual formulations, they may represent a promising approach for long-term B12 management, particularly in patients with impaired absorption or in resource-limited settings

However, doses above 2.4 mg showed diminishing returns due to increased gastrointestinal side effects, including nausea, vomiting, and diarrhea

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