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Eur J Neurosci (2000) 12(10):37218.10.1046/j.1460-9568.2000.00229.x 12 CarneyMWRavindranARinslerMGWilliamsDG

Conclusion and future perspectives Remedial delivery of various therapeutic agents to the brain is frequently impeded due to BBB, which is the chief obstacle in the treatment of CNS disorders

Methodological approaches to exploring epileptic disorders in the human brain in vitro

Finally, prospects for ferroptosis-based interventions and future directions point to several promising treatment avenues, including regulating iron homeostasis via chelators or TfR1/FPN modulation, using antioxidants and lipid peroxidation inhibitors to target GPX4 and ACSL4, or employing gene therapies and stem cell/exosome approaches to combat ferroptosis