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In this pathway, energy and acetyl-coA are produced, each cycle of the fatty acid chain is shortened by two carbons, and the released acetyl-coA then enters the citric acid cycle, during which further energy is produced [12]

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Los efectos secundarios en la L-carnitina Tal y como se describe en los prrafos anteriores, el consumo de L-carnitina es seguro, de hecho, el cuerpo la requiere para poder oxidar el tejido graso, utilizndolo como fuente de energa

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Moreover, the potential of personalized medicine in managing oxidative stress-related neurodegeneration is gaining momentum: genetic variants in the Nrf2 signaling pathway or SIRT1-mediated deacetylation affecting astrocytic GSH synthesis (e.g., regulating glutamate cysteine ligase catalytic subunit expression), combined with biomarkers like individual GSH levels and Nrf2 activity, could enable tailored interventions

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GSH, the reducing substrate of GPX4 activity, is indispensable for preventing ferroptosis (42)

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