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The dual MEK/FLT3 inhibitor E6201 exerts cytotoxic activity against acute myeloid leukemia cells harboring resistance-conferring FLT3 mutations
Brain-derived neurotrophic factor (BDNF)-induced synthesis of early growth response factor 3 (Egr3) controls the levels of type a GABA Receptor4 subunits in hippocampal neurons
Endometriosis commonly causes bloating (endo belly), constipation, diarrhea, and nausea
This resistance is further exacerbated by reduced ATP production, accumulation of reactive oxygen species (ROS), and activation of subclinical inflammatory pathways (Rakshit et al., 2014
