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The compound functions as a synthetic D-retro-inverso peptide carrying a shortened version of the FOXO4 segment that binds to p53, acting as a competitive inhibitor of this critical protein-protein interaction

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These findings positioned FOXO4-DRI as a specialized research tool for investigating senescence-associated signaling, stress response pathways, and cell fate determination in aging models

Warfarin is an anticoagulant that is difficult to use because of the wide variation in dose required to achieve a therapeutic effect, and the risk of serious bleeding