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5.1 Regulation of HSPs in energy metabolism In cold environments, cells activate metabolic processes to increase energy production and raise their temperature

The regulation of thyroid hormones within the hypothalamic-pituitary-thyroid axis is complex, consisting of multiple feedback and feed-forward loops

In some embodiments, formulations or compositions described herein provide a constant, sustained, extended, delayed or pulsatile rate of release of an active agent into the inner ear environment and thus avoid any variability in drug exposure in treatment of otic disorders

D-Nle-X-Ile NH-(CH 2 )s-CONH 2 analogs block HGF Dimerization HGF needs to form homodimers and/or multimers, prior to its activation of Met (Chirgadze et al., 1999