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The use of mouse embryonic fibroblast (MEF) from single or double KO mice for arrestins 2 and 3 revealed that DOR desensitization induced by DPDPE relies predominantly on arrestin 3 expression suggesting a preferential interaction between DOR and this arrestin isoform (Qiu et al., 2007)

[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Devine C.J., Jr., Somers K.D., Ladaga L.E

The combined logic is: Three receptor pathways at once

Helps in boosting immune function