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MTHFR catalyzes the reduction of 5,10-methylene-THF to 5-methyl-THF, which donates a methyl group to homocysteine via MTR (a vitamin B12-dependent enzyme) to regenerate methionine

Nonetheless, the mechanism behind vitamin D supplementation's beneficial effects on cognitive function and behavior is still unclear [9,10,11]

These proteins are named according to the molecular weight as follows: HSP90, HSP70, HSP60, and HSP27, and the upregulation under stress conditions provides cytoprotection by re-establishing protein homeostasis against several stressors, including exercise [85]