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Following myristoylation, FSP1 localizes to the plasma membrane, where it functions as an oxidoreductase, converting NADPH to coenzyme Q10, which acts as a lipid-soluble antioxidant (58,59)
Of these, Gpx1, localized mainly at the mitochondrial level (16), is the isoform most active in the liver (17)
[DOI] [PubMed] [Google Scholar] 50.Landel AM, Hammond WG, Meguid MM
