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At the crossroads of oxygen and iron sensing: hepcidin control of HIF-2

Rheumatoid arthritis models demonstrate the ability of curcumin to inhibit T helper 17 differentiation via suppression of signal transducer and activator of transcription 3 phosphorylation, with additional evidence showing its regulation of the inc00052/miR-126-5p/protein inhibitor of activated STAT 2 axis through the Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway (Xiao et al., 2022