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As Lee, Cell Metabolism reported, MOTS-c levels increase during metabolic stress, suggesting it serves as an adaptive response mechanism to restore cellular balance
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The regulatory mechanisms involved include that MSM may alleviate steatosis by regulating the antioxidant defense system (enhancing superoxide dismutase, TAC, and glutathione peroxidase) and inhibiting mitochondrial energy metabolism related genes [20]
Some studies suggest that glutathione may help mitigate the oxidative stress caused by antibiotics, potentially providing a protective effect on cells
