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currently, diagnosis is based on symptoms evaluated by the Widespread Pain Index and the Symptom Severity Scale

That lack of energy is known as fatigue, and dealing with it all the time can affect your ability to feel motivated about doing anything, even getting out of bed
The remaining patients have a more severe form of the disease that is usually caused by the inheritance of two different defects (a state known as compound heterozygosity)

Intestinal absorption and concurrent chemical changes of methylcobalamin