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For example, the aged phenotype of muscle stem, adipose mesenchymal stem, and hematopoietic stem cells have been rescued after exposure to the blood of a younger animal using a parabiosis model 174

The research demonstrates that effective doses typically fall within specific ranges [2]: The cagrilintide starting dose in most clinical protocols begins at 0.3 mg weekly, with gradual escalation over 8-12 weeks to minimize gastrointestinal side effects [3]

Advertisement Research ArticleImmunology Open Access | 10.1172/JCI179561 1 Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands

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