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Additionally, in LPS-treated microglia, MT1 activation reduced the toxicity of conditioned media to the dopaminergic DA cell line MES23.5
Reduced levels of mitochondrial proteins such as NADH-ubiquinol oxidoreductase (NDUFB8) and voltage-dependent anion channel (VDAC) were observed in the affected white matter of patients with X-ALD (88), suggesting that mitochondrial content or function is impaired in X-ALD
This is particularly beneficial for individuals with conditions affecting glutathione synthesis
doi:10.1016/j.ctcp.2020.101142 Schwingshackl L, Boeing H, Stelmach-Mardas M, et al
