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As search terms for each database, the following keywords were used: glutamine or glutamine dipeptides or Lglutamine or glutamine supplementation and critical care or critical patients or critical ill or critically ill patients or critical illness or serious illness or seriously ill or intensive care units or intensive care or surgical intensive care unit or SICU or critical care medicine. An additional DOCX file shows this in more detail [see Additional file 1]

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Research has revealed that FSP1 can effectively limit the iron-death by engaging in intricate interactions with regulatory pathways [65, 66]