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Figure 6 Crystal structures of IRAP were recently solved (Hermans et al., 2015

However, the specific mechanisms within this complex network remain to be clearly elucidated

doi: 10.1136/bmj.304.6833.1010 442 CleareAJBearnJAllainTMcGregorAWesselySMurrayRMet al

The Kennedy pathway may also be accelerated to compensate for the inhibition of fatty acid synthesis 60