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Am J Clin Nutr 68 : 11041110 Bunn P, Paoletti P, Niyikiza C, Rusthoven J, Nelson K, Hanauske AR, Stabler S, Calvert AH, Allen R (2001) Vitamin B12 and folate reduce toxicity of Alimta (Pemetrexed Disodium, LY231514, MTA), a novel antifolate/antimetabolite

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Table: Early vs Advanced Symptoms of Vitamin B12 Deficiency Not everyone experiences every symptom, and symptoms often develop gradually over months or years