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In db/db mice, the administration of BHB was shown to increase the levels of autophagy markers, including LC3 (Map1lc3a), p62 (Sqstm1), and beclin (Atg6), as well as enhance autophagic flux in the kidneys [9]

The large international consortium (with members from US, Canada, Australia, Germany, France, Italy, UK, Poland, Netherlands, Sweden, Norway, Finland, Denmark, Iran, Russia, Israel, Mexico, Peru, Nepal, India, South Africa, China, and Switzerland) published an article in the NEJM last year sharing results from a study that pooled and harmonized individual-level data from 112 cohort studies conducted in 34 countries and 8 geographic regions (1,518,028 participants) to evaluate the regional and sex-specific prevalence of 5 modifiable risk factors and their effect on cardiovascular disease and mortality

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Toward a theory of childhood learning disorders, hyperactivity, and aggression