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In HFD-induced NAFLD rats, the hepatoprotective effect of Jiaogulan (Gynostemma pentaphyllum (Thunb.) Makino) has been correlated with specific modulations of the gut microbiota (e.g., a reduced Firmicutes/Bacteroidetes ratio, increased Lactococcus, decreased Ruminococcus) and the preservation of intestinal barrier integrity, pointing to microbiota-mediated pathways as a likely component of its action [133]

However, attributing the intolerance to a specific agent within the combination cream remains challenging

Crystal structure of the Ate1 arginyl-tRNA-protein transferase and arginylation of N-degron substrates

Rev Food Sci Qual Manag