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14 However, a 2025 study found that women with PCOS had higher homocysteine levels, a greater frequency of hyperhomocysteinemia compared to controls, and were also more likely to have MTHFR C677T + A1298C, and compound heterozygous variants

Your GP or practice nurse should periodically review whether injection frequency remains appropriate and assess clinical response

If a person has a liver disorder, for example liver disease, then the liver is unable to store vitamin B12 and this can lead to a B12 deficiency

Clavulanic acid Concerns over the antibiotic activity of ceftriaxone led to the study of clavulanic acid, a -lactamase inhibitor that is a structural analog of ceftriaxone and also enhances GLT-1 expression, but lacks antibiotic activity and has better brain penetrability and oral activity [387]