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A key mechanism involves stimulating cytokine secretion by immune cells

The copper peptide uglies typically manifest as: Increased breakouts (microcomedones being pushed to the surface faster) Temporary redness or irritation A rough, uneven texture Skin that looks "tired" or dull for a few weeks If this is true purging, it should resolve within four to six weeks, which aligns with your skin's natural renewal cycle

[DOI] [PMC free article] [PubMed] [Google Scholar] 166.Boehler C.J., Raines A.M., Sunde R.A

Administration considerations How you administer GHK-Cu affects how quickly you use your 100mg supply and how effectively the peptide works