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The acetyl group completely shields the thiol group, preventing it from oxidation to volatile sulfur compounds

To counteract amyloid fibril formation that occurs with human Amy, a pair of helix-stabilizing mutations (N14E and V17R) were incorporated into Cagri 2

Individuals with asthma should exercise caution, as inhaled glutathione has been reported to trigger bronchospasm in some asthmatic patients, though this is less relevant for oral supplementation