glutathione dmso and cataracts Unbalanced redox status network as an early pathological event in congenital Cyclic cell-penetrating peptide-engineered ceria nanoparticles

10.1016/j.biomaterials.2011.07.078 19 Belhadj-TaharH.ChenJ.SongP.ZhaoJ.QuanM.LiC.et al (2019)

In addition, dysregulated -KG flux from normal reductive anabolism via the TCA cycle toward R-2-HG production has been associated with other metabolic flux impairments and disrupted redox balance 119,120 (Fig

SARS-CoV-2 infection generates massive ROS production and the excessive oxidative damage is responsible for cytokine storm, undermined immunity, tissue damage and severe lung disease causing ARDS and death (Silvagno et al., 2020)

GSSSG deactivates the NF-B signaling pathway, which results in downregulation of proinflammatory gene expression in retinal cells including microglia