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Description
These effects occur through inhibition of NF-kappaB nuclear translocation and suppression of MAPK signaling pathway activation, reducing transcription of inflammatory mediator genes

Genomic Stability: Lower incidence of chromosomal mutations in aging models 3

The Clinical Context When Novo Nordisk developed CagriSema (cagrilintide combined with semaglutide), tolerability became a significant consideration in their trials

doi: 10.1002/lsm.22170
