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With 3.6 million people in England alone suffering from Type 2 diabetes and a shocking new study revealing that those diagnosed before age 40 face a fourfold higher risk of premature death, the need for safe, effective, and affordable solutions has never been greater

VDR agonists such as paricalcitol exhibit promising translational potential, although further studies are needed to clarify their mechanisms and clinical indications

369 doi: (Published 24 April 2020) Cite this as: BMJ 2020;369:m1319 Muhajir Mohamed, consultant haematologist and associate professor of medicine1 2, Joel Thio, medical intern3, Remy Susan Thomas, medical intern4, Jehan Phillips, general practitioner5 1 Department of Medicine, Launceston General Hospital, Australia 2 University of Tasmania, Launceston Clinical School, Launceston, Australia 3 Department of Medicine, Launceston General Hospital, Australia

Nanoparticle-Mediated Immunogenic Cell Death Enables and Potentiates Cancer Immunotherapy