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(II) improvements in traditional drugs: Donafenib offers enhanced overall survival compared to sorafenib [256], and Ticlopidine provides additional benefits [254]

LDH activity was determined in coronary effluents

Further investigation is needed to comprehensively grasp the regulatory mechanisms and molecular functions of mNADK, given that PTMs can disrupt substrate binding and affect enzyme activity, thereby impacting mNADK's functionality

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