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It facilitates the breakdown of proteins in extrahepatic tissues, particularly skeletal muscle, under specific conditions (e.g., prolonged exercise or fasting)

Geffroy G, Benyahia R, Frey S, Desquiret-Dumas V, Gueguen N, Bris C, Belal S, Inisan A et al (2018) The accumulation of assembly intermediates of the mitochondrial complex I matrix arm is reduced by limiting glucose uptake in a neuronal-like model of MELAS syndrome

Abbreviations: BMI body mass index, -HB -hydroxybutyrate, CESD-R-20 - center for epidemiologic studies depression scale-revised, CRP C-reactive protein, HbA1c - glycated hemoglobin, HDL - high-density lipoprotein, KD ketogenic diet, LDL - low-density lipoprotein, MCT - medium-chain triglycerides, MCT-KD - medium-chain triglyceride ketogenic diet, MDS-UPDRS - Movement Disorder Society Unified Parkinsons Disease Rating Scale, PAS - Parkinsons anxiety scale, PD - Parkinsons disease, PD-MCI - Parkinsons disease with mild cognitive impairment, VHI - voice handicap index Moreover, certain studies encounter challenges related to the accuracy of self-reported data, such as food diaries and questionnaires, which can impact the reliability of findings

Acta Myol 30(1):1623 Jun JC, Rathore A, Younas H, Gilkes D, Polotsky VY (2017) Hypoxia-inducible factors and cancer