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doi: 10.1016/j.neurol.2016.03.006 132 LehikoinenJ.NurmiK.AinolaM.ClancyJ.NieminenJ
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The advice is to investigate and treat the vitamin B12 deficiency in the normal way, following clinical guidelines, and to continue the metformin

B12 helps boost your metabolism by converting fats and proteins into energy
