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Description
The rationale was that direct delivery to the joint would maximize local efficacy while minimizing systemic exposure
doi: 10.1074/jbc.272.43.27218
In short: While B12 shots are FDA-approved for treating serious conditions such as anemia and malabsorption, they are also used in wellness settings to help people with subclinical deficiencies feel more focused and energized

This delayed peak explains why some people experience a temporary dip in appetite suppression during the first month after switching
