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B vitamins are involved in energy production, metabolism, nervous system function, and overall cellular health

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In vivo models of autoimmune cystitis have been used to experimentally show that inhibition of TNF- diminishes inflammation within the bladder by disrupting the triggering of mast cells [26,27,28]

However, full effects on metabolism and other areas may take 4-6 weeks as it takes time for levels to build up in the body
