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Janus Kinase (JAK) Inhibitors: Leading the Revolution JAK inhibitors have emerged as one of the most promising new treatments for vitiligo

This compound is a human Rho kinase inhibitor that has been approved for therapy in cerebral vasospasm and glaucoma [273] with the capacity to cross the BBB and exerts neuroprotection in MPTP-treated mice [274]

Rosenthal DI

Lurie when he was an Associate Commissioner at FDA, and previously cited by FDA Commissioner Makary, most CRLs (87 percent) issued between 2008 and 2013 cited important clinical deficiencies in safety, efficacy, or both
