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The increase in AMP concentrations relieves the inhibition of PFK-1 by ATP, activating glycolysis
Stimulation of glucose transport in osteoblastic cells by parathyroid hormone and insulin-like growth factor I

Mechanistically, these changes appear to coincide with elevated NAD+ and activation of metabolic gene programs consistent with increased energy expenditure
b , Population doubling rate in 293 T cells transfected with DdCBEs, n = 3 biological replicates
