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However, although the primary outcome measure was not met, when patient groups were split based on t-PA treatment or not, the group that did not receive t-PA had significantly better outcomes and smaller infarct volume with NA-1 treatment

It was found that when the nAb titer is 1:1, it limits the process of transmitting information from the AAV vector [100], while at a titer of 1:5, hepatic transduction is completely blocked

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