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The protonation of anionic ATRA (p K a ~6.06.5) within the ATRA/PEI ion-complexes led to the dissociation of the ionic bonds at pH values lower than the pKa 48 , which may trigger a faster release

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Nrf2 regulates key components of anti-ferroptotic pathways, positioning it as a central modulator of lipid peroxidation and ferroptosis (62)

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