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One of the biomarkers is 8-hydroxy-2-deoxyguanosine (8-OHdG), generated by the oxidation of the deoxyguanosine at the C-8 position (Figure 1)

Hypertension exacerbates cerebrovascular oxidative stress induced by mild traumatic brain injury: Protective effects of the mitochondria-targeted antioxidative peptide SS-31

Further discussion of key modulators of CR-response in metabolic reprogramming and immune suppression in Table 1 can be found in the Suppl

Evolution 63, 30163022
